News

2018/10/04
Spectacular results on breast cancer with Peking University Peoples Hospital
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2018/09/25
Bertrand de Poly Jury for Les Echos E-Health 2018 Award
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2018/07/01
LLTECH laureate of the ECARE tour 2018
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2018/05/01
Meet us at BIO 2018
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2018/01/05
LLTech at Photonics West 2018 – 27 January – 1 February 2018
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The Light-CT Scanner is a high-resolution imaging device for subcellular-level biological tissue imaging. It performs non-invasive and non-destructive real-time optical biopsy.

In depth microscopic tissue visualization in a fast, non-destructive manner without the use of contrast agents is needed to enable real-time diagnostic and biopsies evaluation when the patient is in the surgical or radiology suite..

The Light-CT system is a high-resolution (1µm 3D) pathology scanner that performs optical slicing beneath the tissue surface at selected depths. Using two different acquisition methods, called Full-Field Optical Coherence Tomography (FFOCT) and Dynamic Cell Imaging (DCI). Light-CT produces images showing both the tissue architecture and the intracellular activity data without sample processing or staining.

This multi-modal information comes from the system abilities to detect variations of light retro-diffusion and to record metabolism-induced residual intracellular movements of freshly excised tissue.

In the context of tissue imaging for cancer diagnosis, LLTech anticipates the following benefits:

  • Better image quality: the full-field OCT technology employed by the Light-CT Scanner is the sole technique to offer axial resolution (i.e. in the vertical, z-axis) of 1 µm, which gives the best image clarity and precision.
  • Speed (rapidity of diagnosis): the technology currently enables image capture on a 1 cm² region of tissue in 4 to 5 minutes, thereby enabling immediate quality control of biopsies.
  • Avoiding patient recall in the event of complex biopsies that require hospitalization and/or anesthesia.
  • Non-destructive technology that allows reuse of the biopsy: no need for dyes, contrast agents or tissue freezing
  • Analysis can be carried out remotely
  • Ease of use: LLTech products can be employed directly. No calibration or complex set-up procedure is necessary. User training is completed in under half a day.

 

Light-CT Scanner technical data

Dimensions 310 x 360 x 700 mm
Weight 20 kg
Main input voltage, frequency and current 100 to 240 V ~AC, 50 to 60 Hz, 3A
Compliance to international standards OC IEC 61010-1
OC IEC 61326-1
CE – Research Use Only
Axial resolution 1 µm
Transverse resolution 1.5 µm
Field of view 1.3 mm x 1.3 mm
Maximum Field of view (with mosaicing) 25 mm diameter
Maximum sample size 27 mm diameter x 5 mm height
Penetration depth 200 µm to 1 mm
Frame rate 75 Hz
Snapshot camera resolution
(widefield sample image)
50 µm
Image formats DICOM; export JPG, TIFF, PNG
Included in package Light-CT Scanner unit
PC
High-end screen
Acquisition and viewing software

The acquisition software was developed in collaboration with Ecole CentraleSupélec.

Intended Use Statement: The Light-CT Scanner is intended to acquire, store, retrieve, display, and transfer optical coherence tomography images of unsectioned excised surgical tissue for review by physicians to assist in forming a clinical judgment. The Light-CT Scanner is not intended as a primary means of diagnosis. The Light-CT Scanner is certified for research use only.